Joint Support Supplement

Curcumin C3® Complex is a patented herbal extract obtained from the dried rhizomes of Curcuma longa (turmeric) standardized to contain 95% bioactive curcumin, bisdemethoxycurcumin, and demethoxycurcumin - collectively referred to as “curcuminoids”. 

Unlike generic turmeric extracts, Curcumin C3® Complex exhibits vastly superior absorption and upwards of 200x greater bioavailability [1, 2].

Clinical evidence suggests that curcuminoids have ubiquitous roles in the body, affecting vital biological processes such as immune function, detoxification, metabolism, stress response, neuroplasticity, joint integrity, digestion, etc [3].

For example, a recent double-blind, placebo-controlled trial found that subjects taking Curcumin C3® Complex  for 8 weeks had significantly greater reductions in proinflammatory cytokine serum concentrations than those taking a placebo [4].

These results are consistent with the findings of a recent meta-analysis of the anti-inflammatory actions of curcumin in clinical studies [5].

FruiteX-B® is a patented boron-based mineral supplement (calcium fructoborate) that acts as a superoxide ion scavenger and anti-inflammatory agent [6]. 

A growing body of peer-reviewed, published clinical research indicates that the calcium fructoborate significantly reduces serum levels of the C-reactive protein in humans, suggesting that this unique plant–mineral complex may contribute to bone health by controlling the inflammation associated with loss of bone mineral density [7, 8].

Further evidence suggests that calcium fructoborate has beneficial effects on blood lipid profiles and cardiovascular function [9].

The phytochemicals in Boswellin® Super actively inhibit the actions of pro-inflammatory molecules, notably 5-lipoxygenase (5-LO), human leukocyte elastase (HLE), cathepsin G (catG), and acetylcholinesterase (AChE) [10,11].

In fact, multiple clinical studies have shown that Boswellin® significantly reduces blood biomarkers of inflammation, resulting in improvement in joint discomfort and function [12].

While there are many types of collagen, type-II collagen in particular is crucial for supporting the function and integrity of joint-related connective tissues. Research shows that collagen production drops by about 25% at the age of 40; by the age of 60, it falls to 50% [13].

There is a growing body of clinical evidence showing the promising benefits of undenatured type-II collagen peptides (specifically UC-II®) for bolstering joint integrity, as well as alleviating joint discomfort and increasing range of motion/flexibility in joints [14].

Piperine, the primary bioactive constituent in black pepper (Piper nigrum), is known as a “bioenhancer” since it helps with the bioavailability of molecules that are typically poorly absorbed or extensively metabolized in the liver [15, 16]. Hence, patented BioPerine® assists with the absorption and efficacy of other active ingredients in Transparent Labs Joint Support.